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Logo SFC Process Chromato
Your project
Logo SFC Process Chromato
Your project

CHROMATOGRAPHY
Integrate supercritical CO2 purification into your process

Purify your molecules without toxic chemical solvents
A fast, cost-effective process
Separation of closely related molecules
The method in detail
Let's talk about your project
Purification with supercritical CO2
is the guaranteed method
for separating molecules without using organic solvents.
Chromatography, a formidable purification and production tool
Finalize your purification process with supercritical CO2 chromatography, enabling you to separate, select and collect one or more molecules of interest from the preparative scale. It can also be used to analyze the composition of a complex mixture.
Let's talk about your project

Whether you're in the testing or production phase

we have the solution

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Preparatory scale

SFC PREP

Standard range from 100ml to 2L

Discover the range
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Production scale

SFC PROD

Standard range from 2x5L to 2x100L

Discover the range

Whether you are in the preparation or production phase

we have the solution

Semi prep
sfc 30

SFC 30

Information
Column diameter :
CO2 flow :
CO2 co-solvent :
30mm
Up to 150g/min
Up to 50ml/min
Discover the model
Prep
sfc 50

SFC 50

Information
Column diameter :
CO2 flow :
CO2 co-solvent :
50mm
Up to 1 000g/min
Up to 400ml/min
Discover the model
Prep
sfc 50

SFC 100

Information
Column diameter :
CO2 flow :
CO2 co-solvent :
100mm
Up to 2500g/min
Up to 600ml/min
Discover the model

SFC Process expertise
to bring your project to fruition

01.

Specifications

  • Assessing your needs
  • Definition of technical specifications
  • Price offer
  • Specification validation

02.

Design

  • PID (Piding Instrumentation Diagram)
  • PLC program
  • 3D model design and validation
  • Sizing
  • Bill of Materials

03.

Manufacturing

  • Made in France
  • Quality management system
  • Qualified and validated subcontractors
  • FAT validation (in-house validation and testing)

04.

Installation

  • Delivery
  • SAT validation (validation and testing at your plant)

05.

Support

  • Service international
  • Installation, commissioning
  • Training and support
  • Maintenance and improvement
  • SERVICE

The advantages of supercritical CO2 purification

Fast

It reduces the number of steps and therefore the cost of purification, by eliminating or greatly reducing post-processing steps such as the elimination of elution solvents.

Scalable

Our systems are designed to be modular, scalable and adaptable to your production needs. They are also designed from laboratory to industrial scale. industrial scale.

bill

Productivity

Solvent management and reprocessing are greatly reduced, thus greatly reducing the OPEX and environmental cost of a process.

Own

Large quantities of samples can be purified while reducing or completely eliminating the consumption of toxic chemical solvents. CO2 is a natural, non-toxic, inert and odorless solvent, unlike petrochemical solvents.

Safe

Supercritical CO2 is a safe and effective solvent, without the risks associated with other solvents used for purification, such as volatile and potentially explosive organic solvents (like ethanol, for example). What’s more, supercritical CO2 can be easily separated and recycled, making it an environmentally-friendly and economical choice for purification.

Chromatography with SFC Process

SFC Process builds state-of-the-art, high-performance supercritical phase chromatography equipment for R&D laboratories and industrial scale-up. The solutions implemented by SFC Process enable a drastic reduction in the use of co-solvent, thanks to the development of chromatographic equipment capable of working on a range of CO2 densities never before evaluated.

Research and Development (R&D)

Do you have a specific need?

SFC Process has a research and development laboratory to carry out your feasibility studies in partnership with Reach Separation, which is equipped with the
SFC 30
 and develop tomorrow’s technologies.

Would you like to test your biomass before taking the plunge? Our laboratory is equipped with several pilots, so we can offer you a top-quality service and full support for scale-up, from laboratory scale to pilot scale, producing your first batches.

Request an appointment

Schedule your appointment

Discover how SFC Process will take your purification process into a new era

Book a meeting with our engineers and chemists, and together we’ll find the best solutions for setting up or improving your extraction process.

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★★★★★ 4.5/5
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What is chromatography used for?
Chromatography is based on the use of a supercritical fluid as the mobile phase or eluent. CO2, in its supercritical form, has density and hydrophobicity characteristics that can be modulated according to pressure. It’s these characteristics that come into play during SFC purification. As CO2 is a gas at atmospheric pressure and ambient temperature, the richer the eluent composition in CO2, the more economical it is to obtain “dry” compounds of interest.
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SFE PROCESS 2023

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